When you run Replicator for the first time on your machine, a message box appears:

✓Solution

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Summary

Users running Windows 10 v1703 Creators Update, Windows 8.1, Windows Server 2012 and others will experience this problem after installing Replicator for first time ever on the computer.

Details

Replicator didn't create the folder "%LOCALAPPDATA%\Karen's Power Tools\Replicator" because it thought the folder had already been created.  The old work-around was to manually create the folder.  

Affected

v3.7.5, v3.7.4, v3.7.3, v3.7.2, v3.7.1, v3.7, v3.6.9

Fixed

First fixed in Replicator v3.7.6 released May 25, 2020

Karen's Replicator

https://www.karenware.com/powertools/karens-replicator-backup-utility